Cheapest GLP-1 Providers of April 2026

For brand-name: Orforglipron via LillyDirect at $149/month is the cheapest FDA-approved GLP-1 available. For compounded semaglutide specifically: Ro, Henry Meds, or Noom at $149/month. For Medicare patients: the Bridge program at $50/month copay. The Sesame + third-party pharmacy route can potentially go lower (~$129/month) but requires self-management.

Wegovy is a brand-name product made by Novo Nordisk with FDA approval as a finished injectable. Compounded semaglutide uses the same active ingredient but is mixed by compounding pharmacies, which don't bear the costs of clinical trials, FDA approval for the finished product, or brand marketing.

Prices have been trending down. In early 2025, $200/month was the floor. By April 2026, compounded semaglutide is at $149/month, and orforglipron is expected to launch at $149/month upon FDA approval. Medicare patients will pay just $50/month through the Bridge program when it launches in July 2026. Competition continues to push pricing lower, and GoodRx's $39/month telehealth subscription suggests the access fee component will compress further. We update this page monthly to reflect current pricing.

Most providers on this list are transparent about pricing. Watch for: separate consultation fees (rare now), shipping charges, required lab work not included in pricing, and mandatory program fees on top of medication costs. We flag all hidden costs in our reviews.

Yes. No provider (except Calibrate) locks you into a long-term contract. You can switch at any time. Share your dosing history with your new provider to maintain your titration schedule and avoid starting over.

For brand-name: Orforglipron via LillyDirect at $149/month is the cheapest FDA-approved GLP-1 available. For compounded semaglutide specifically: Ro, Henry Meds, or Noom at $149/month. For Medicare patients: the Bridge program at $50/month copay. The Sesame + third-party pharmacy route can potentially go lower (~$129/month) but requires self-management. ### Why is compounded semaglutide so much cheaper than Wegovy? Wegovy is a brand-name product made by Novo Nordisk with FDA approval as a finished injectable. Compounded semaglutide uses the same active ingredient but is mixed by compounding pharmacies, which don't bear the costs of clinical trials, FDA approval for the finished product, or brand marketing. ### Is $149/month the cheapest GLP-1 will get? Prices have been trending down. In early 2025, $200/month was the floor. By April 2026, compounded semaglutide is at $149/month, and orforglipron is expected to launch at $149/month upon FDA approval. Medicare patients will pay just $50/month through the Bridge program when it launches in July 2026. Competition continues to push pricing lower, and GoodRx's $39/month telehealth subscription suggests the access fee component will compress further. We update this page monthly to reflect current pricing. ### Are there hidden fees I should watch for? Most providers on this list are transparent about pricing. Watch for: separate consultation fees (rare now), shipping charges, required lab work not included in pricing, and mandatory program fees on top of medication costs. We flag all hidden costs in our reviews. ### Can I switch providers to get a lower price? Yes. No provider (except Calibrate) locks you into a long-term contract. You can switch at any time. Share your dosing history with your new provider to maintain your titration schedule and avoid starting over.