Best Of — March 2026

Best GLP-1 Weight Loss Programs of April 2026

We ranked the 10 best GLP-1 weight loss programs by price, clinical protocols, and verified patient outcomes. Updated April 2026 — no paid placements.

10providers reviewed and ranked

Updated March 28, 2026 · Next review: March 28, 2027

Sarah ChenLead Health Editor

Editorial independence: Revenue never influences our rankings. Providers do not pay for placement. All 10 providers evaluated using 6 scoring criteria. Read our methodology

Editorially independent · Rankings never paid

Our top picks

89/100

Price-conscious patients wanting affordable orforglipron from an established, trusted platform with coaching support.

From $149/month (compounded semaglutide) or branded options via insurance/mo

87/100

FORM Health

Patients with complex metabolic needs, multiple comorbidities, good insurance, or who want specialist-level care with the full range of treatment options.

From $199/month program fee + medication/mo

82/100

Found

Patients wanting behavioral support, community, and video consultations alongside GLP-1 treatment at a moderate price point.

From $159/month (orforglipron) or $159-$299/month (branded semaglutide/tirzepatide)/mo

How We Evaluate

Factor	Weight	What We Measure
Price transparency	25%	Published pricing, hidden fees, billing clarity
Clinical protocols	20%	Prescriber credentials, titration approach, lab requirements
Patient outcomes	20%	Verified review scores, reported weight loss timelines
Access & convenience	15%	States served, wait times, refill process
Support quality	10%	Ongoing check-ins, dietitian access, messaging response
Value for money	10%	Price relative to what you get

Revenue never influences these rankings. Read full methodology

What Is Changing in 2026

The GLP-1 telehealth market is undergoing significant changes in 2026. Before diving into rankings, here is what is reshaping the landscape:

Compounded semaglutide is under pressure. FDA enforcement against 30+ compounding pharmacies is contracting the market. Some providers have already exited compounding; availability may continue to narrow.
Orforglipron is expected soon (April 2026). The first oral daily GLP-1 — a pill, not an injection — at an announced price of $149/month. FDA approval is expected around April 2026 and would make it the leading affordable brand-name option.
Hims exited compounding entirely. Now brand-only, operating as an authorized Novo Nordisk distributor. A significant change from its former compounded offering.
Medicare Bridge expected (July 2026). Medicare is scheduled to cover GLP-1s for weight loss at a $50/month copay starting July 1, 2026 — which would be the biggest access expansion in the category's history.
Oral Wegovy available. Brand-name semaglutide in pill form at $199-$299/month through select providers.

These changes are reshaping every provider on this list.

Best OverallGLP-1Independent Review

Ro

89/100

From $149/month (compounded semaglutide) or branded options via insurance/mo

Ro combines the lowest compounded semaglutide pricing ($149/month, tied with Henry Meds and Noom) with metabolic health coaching included at no extra charge. That coaching inclusion — something most competitors charge extra for or skip — is the differentiator that keeps Ro at the top. Over 1 million patients served, established platform. Ro is also preparing for orforglipron and expanded branded options.

Compounded semaglutideBrand WegovyBrand ZepboundOral Wegovy

Monthly cost (compounded semaglutide): $149
Monthly cost (branded semaglutide): Via insurance/cash-pay
Consultation: Free
Shipping: Free
Coaching: Metabolic health coaching included
Lab testing: Not included
Consultation type: Async only

Pros

Lowest compounded semaglutide pricing (tied) with coaching included
Metabolic health coaching at no extra cost
Established platform with millions of patients
Brand Wegovy and Zepbound also available

Cons

Async-only — no video consultations
No lab testing included
Branded semaglutide significantly more expensive than orforglipron
Limited to GLP-1 medications only (no combination therapy)

Visit Ro

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients with complex metabolic needs, multiple comorbidities, good insurance, or who want specialist-level care with the full range of treatment options.GLP-1Independent Review

FORM Health

87/100

From $199/month program fee + medication/mo

FORM Health remains the most clinically rigorous option on this list. Every clinician is a board-certified obesity medicine specialist, a registered dietitian is included, and they offer the broadest medication toolkit — including combination therapy, oral Wegovy, and Wegovy HD. Their insurance-first approach means many patients pay significantly less than the sticker price. The transition away from compounding was seamless because FORM always emphasized clinical depth over cheap medication.

Brand WegovyBrand Wegovy HDOral WegovyBrand ZepboundOrforglipronContravephentermine-topiramatemetformin

Program fee: $199/month
Medication: Additional (varies by medication and insurance)
Consultation: Video with obesity medicine specialists
Dietitian: Registered dietitian included
Lab testing: Recommended and coordinated
Insurance: Accepted for clinical visits, active PA support

Pros

Every clinician is a board-certified obesity medicine specialist
Registered dietitian included in program
Broadest medication toolkit including combination therapy and Wegovy HD
Insurance accepted for clinical visits with prior auth support

Cons

Higher total cost ($199 program + medication)
Not available in all states
Longer onboarding process
May have waitlists in high-demand areas

Visit FORM Health

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients wanting behavioral support, community, and video consultations alongside GLP-1 treatment at a moderate price point.GLP-1Independent Review

Found

82/100

From $159/month (orforglipron) or $159-$299/month (branded semaglutide/tirzepatide)/mo

Found occupies the middle ground between bare-bones medication delivery and full clinical programs. At $159/month for orforglipron, you get video consultations with board-certified obesity medicine specialists, coaching, and community support — $10/month more than Ro, but with video consultations instead of async-only. Found's transition to branded medications and orforglipron has been clean, and the community support feature is a genuine differentiator for patients who value peer connection.

OrforglipronBrand WegovyBrand ZepboundOral Wegovy

Monthly cost (orforglipron): $159
Monthly cost (branded semaglutide): $159–$299
Consultation: Video with obesity medicine specialists
Coaching: Included
Community: Access included
Lab testing: Not included
Shipping: 5-7 business days

Pros

Board-certified obesity medicine specialists
Video consultations (not async-only)
Coaching and community support included
Orforglipron + branded options available

Cons

$10/month more than Ro for orforglipron
Slower shipping (5-7 business days)
No lab testing
Coaching quality may vary

Visit Found Compare Found vs Calibrate

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients concerned about long-term weight maintenance who want structured behavioral support alongside GLP-1 medication.GLP-1Independent Review

Noom

80/100

From $149-$499/month (branded); orforglipron expected at $149/month upon FDA approval/mo

Noom brings something unique: a decade-long track record in behavioral change combined with GLP-1 medication. Their CBT-based curriculum (daily 10-15 minute lessons), personal coaching, and group sessions address the psychological side of weight loss — which matters because GLP-1 medications work best with lifestyle changes and weight regain is common after stopping. The anticipated addition of orforglipron at $149/month (pending FDA approval, PDUFA April 10, 2026) is expected to make Noom Med significantly more accessible.

Brand WegovyBrand Zepbound; Orforglipron expected upon FDA approval (PDUFA April 102026)

Monthly cost (orforglipron, expected): $149 (pending FDA approval)
Monthly cost (branded): $299-$499
Consultation: Video required
Coaching: Personal coach + group sessions
CBT curriculum: Daily lessons included
Lab testing: Not included
App access: Full Noom app included

Pros

Unique GLP-1 + established CBT behavior-change curriculum
Video consultations required (not async-only)
Personal coach and group coaching included
Expected competitive orforglipron pricing ($149/month once FDA-approved — PDUFA April 10, 2026)

Cons

Cannot opt out of coaching to lower cost
No published clinical trial data for combined GLP-1 + CBT program
No lab testing
Branded medication pricing on the higher side

Visit Noom Compare Noom vs Sequence

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients with insurance-covered GLP-1 medications wanting affordable ongoing telehealth management, or GoodRx users who already trust the platform.GLP-1Independent Review

GoodRx Care

78/100

From $39/month subscription + medication/mo

GoodRx Care offers a distinctive model: a $39/month telehealth subscription that covers unlimited consultations, separate from medication cost. Once orforglipron is approved (PDUFA April 10, 2026), patients would pay $188/month total ($149 orforglipron + $39 subscription) — competitive with Ro or Hims for the same pill. For patients on insurance-covered branded medications, the $39/month subscription is one of the cheapest paths to ongoing provider management. GoodRx's pharmacy discount network is also an advantage for price-shopping brand medications.

Brand WegovyOral WegovyBrand Zepbound; Orforglipron expected upon FDA approval (PDUFA April 102026)

Subscription: $39/month
Orforglipron: $149/month (additional)
Branded medication: Varies (via insurance or pharmacy)
Consultations: Unlimited, included in subscription
Coaching: Not included
Lab testing: Not included
Pharmacy discounts: GoodRx network included

Pros

Unlimited consultations at $39/month
GoodRx pharmacy discount network integrated
Good for patients managing insurance-covered medications
Orforglipron available

Cons

Two-part billing (subscription + medication)
Total orforglipron cost ($188/month) higher than competitors
No coaching or behavioral support
Relatively new weight loss offering

Visit GoodRx Care

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients who want brand-name oral Wegovy (semaglutide pill) from a large, publicly traded platform, or budget-conscious patients selecting the $149 orforglipron option.GLP-1Independent Review

Hims

76/100

From $249/month (oral Wegovy) or $299/month (injectable Wegovy)/mo

Hims is the largest DTC telehealth platform on this list and the only publicly traded company (NYSE: HIMS). The Novo Nordisk partnership gives Hims exclusive access to oral Wegovy at scale — an option for patients who want brand-name semaglutide in pill form without injections. The tradeoff: Hims is now significantly more expensive than it was during the compounding era. At $249-$299/month with no coaching or labs, the value proposition rests entirely on brand trust and oral Wegovy access.

Brand WegovyBrand Wegovy HDOral WegovyOrforglipron ($149/month)Brand Zepbound

Monthly cost (oral Wegovy): $249
Monthly cost (injectable Wegovy): $299
Monthly cost (orforglipron): $149
Consultation: Free, async only
Shipping: Free
Coaching: Not included
Lab testing: Not included

Pros

Publicly traded with SEC oversight and audited financials
Novo Nordisk partnership for oral Wegovy
Massive operational scale
Orforglipron at competitive $149/month

Cons

Branded semaglutide $100-$150/month more than former compounded pricing
Async-only, no video
No coaching, no labs
Limited to GLP-1 medications (no combination therapy)

Visit Hims Compare Hims vs Ro

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients seeking the most comprehensive, structured weight loss program with specialist oversight, lab monitoring, and good insurance.GLP-1Independent Review

Calibrate

75/100

From $299/month program + medication/mo

Calibrate's year-long metabolic reset program is the most comprehensive on this list — video visits with obesity medicine physicians, lab testing included, 1:1 coaching, and a metabolic health curriculum. The tradeoff is cost: at $299/month for the program alone (plus medication), it remains the most expensive option. Medicare Bridge navigation helps seniors, and strong insurance support can offset medication costs. But the mandatory one-year commitment and high program fee mean Calibrate only makes sense for patients committed to the full clinical experience.

Brand WegovyBrand Wegovy HDBrand ZepboundOrforglipron

Program fee: $299/month
Medication: Additional (varies by insurance)
Consultation: Video with obesity medicine specialists
Lab testing: Included
Coaching: 1:1 coaching included
Commitment: One-year required
Insurance navigation: Full PA support, Medicare Bridge

Pros

Comprehensive year-long metabolic health program
Lab testing included (rare among telehealth providers)
Video consultations with obesity medicine specialists
Active insurance navigation, PA support, and Medicare Bridge

Cons

Highest total cost ($299/month program + medication)
One-year commitment required
Coaching is mandatory (no medication-only option)
Not available in all states

Visit Calibrate Compare Found vs Calibrate

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients with health insurance that may cover GLP-1 medications, wanting specialist-level clinical care with aggressive insurance navigation.GLP-1Independent Review

Sequence

74/100

From $99/month membership + medication/mo

Sequence was founded by obesity medicine specialists and takes an insurance-first approach — they actively work to get your GLP-1 covered. If your insurance covers medication, Sequence's $99/month membership for specialist-level video care is strong value. For cash-pay patients on orforglipron, the two-part billing ($99 + $149) totals $248/month — significantly more than Ro or Noom for the same pill.

Brand WegovyBrand Wegovy HDBrand ZepboundOral WegovyOrforglipron

Membership: $99/month
Medication (cash-pay): $149-$399/month additional
Consultation: Video with obesity medicine specialists
Insurance navigation: Prior auth + appeals included
Lab testing: Recommended

Pros

Founded by obesity medicine specialists
Insurance-first approach with prior auth and appeals
Video consultations with experienced clinicians
Full medication range including Wegovy HD and oral options

Cons

Most expensive for cash-pay ($248-$498/month total)
Two-part billing structure
No published independent outcomes data
Insurance coverage not guaranteed

Visit Sequence Compare Noom vs Sequence

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Patients with strong GLP-1 insurance coverage wanting prescriptions through their own pharmacy, including Medicare patients.GLP-1Independent Review

PlushCare

72/100

From $99/year membership + consultation fees + medication via your pharmacy/mo

PlushCare is a general telehealth platform, not a weight loss specialist. The advantage: video consultations with physicians who can prescribe brand-name GLP-1s through your insurance, filled at the pharmacy of your choice. If you have excellent insurance covering Wegovy, Zepbound, or orforglipron, PlushCare may be the cheapest path to provider management. Available in all 50 states. The Medicare Bridge expansion makes PlushCare a solid option for seniors who want to use their existing pharmacy.

Brand WegovyBrand Wegovy HDBrand ZepboundOrforglipronRybelsus (off-label)Contravephentermine

Membership: $99/year or $19.99/month
Consultation (insured): Copay
Consultation (cash): $129-$249/visit
Medication: Via your pharmacy
Coaching: Not included
States: All 50

Pros

Insurance-based model (potentially cheapest with good coverage)
Video consultations with licensed physicians
Available in all 50 states
Full pharmacy choice

Cons

Generalist physicians, not obesity specialists
No coaching or behavioral support
Consultation fees add up without insurance
Not focused on weight loss

Visit PlushCare Compare PlushCare vs Sesame

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Self-directed, experienced patients who need a prescription and can manage their own care, or patients wanting the cheapest path to an orforglipron prescription.GLP-1Independent Review

Sesame

68/100

From $29-$79/consultation + medication sourced independently/mo

Sesame is a marketplace for affordable telehealth visits, not a weight loss program. You pay per visit ($29-$79), get a prescription, and fill it wherever you choose. Maximum flexibility, minimum hand-holding. In the post-compounding market, Sesame's value proposition has shifted: it is now primarily useful for patients who want a cheap consultation to get an orforglipron prescription ($149/month from any pharmacy) or who have strong insurance and want a one-off prescription.

Brand WegovyBrand ZepboundOrforglipronRybelsusContravephenterminetopiramate

Consultation: $29-$79 per visit
Subscription: None required
Medication: You source independently
Coaching: Not included
Insurance navigation: Not included
Flexibility: Maximum

Pros

No subscription required
Lowest consultation cost ($29-$79)
Full pharmacy and medication choice
Broadest medication access

Cons

You handle medication sourcing and ongoing management
No prior authorization assistance
No coaching or behavioral support
Clinician quality varies

Visit Sesame Compare PlushCare vs Sesame

Ally earns a referral fee from some providers. Rankings are never influenced by revenue. See our methodology →

Side-by-Side Comparison

Provider	Orforglipron	Branded Semaglutide	Tirzepatide	Consultation	Coaching	Labs	Score
1Ro	$149/mo	$149–$299/mo	Available	Async	Included	No	89
2FORM Health	Available	Via insurance	Via insurance	Video (specialist)	Dietitian	Coordinated	87
3Found	$159/mo	$159–$299/mo	Available	Video (specialist)	Included	No	82
4Noom	$149/mo	$299–$499/mo	Available	Video	CBT + coach	No	80
5GoodRx Care	$149/mo (+$39 sub)	Via pharmacy	Via pharmacy	Included in sub	No	No	78
6Hims	$149/mo	$249–$299/mo	Available	Async	No	No	76
7Calibrate	Available	Via insurance	Via insurance	Video (specialist)	1:1 coach	Included	75
8Sequence	$99 + $149/mo	$99 + varies	$99 + varies	Video (specialist)	No	Recommended	74
9PlushCare	Via pharmacy	Via pharmacy	Via pharmacy	Video	No	No	72
10Sesame	$29-$79/visit*	$29-$79/visit*	$29-$79/visit*	Video/Phone	No	No	68

Scroll right to see all columns →

Our Methodology

We evaluated each provider across six weighted categories, totaling 100 points:

Price transparency25%

Clinical protocols20%

Patient outcomes20%

Access & convenience15%

Support quality10%

Value for money10%

Frequently Asked Questions

What is a GLP-1 medication?

What is happening with compounded semaglutide?

Compounded semaglutide — the $149/month option that many budget telehealth providers rely on — is under increasing regulatory pressure in 2026. The FDA has issued enforcement actions against 30+ compounding pharmacies. Hims has exited compounding entirely. Several providers (Ro, Henry Meds, Noom, Found) continue to offer compounded options, but availability may tighten further. [Read our compounding guide](/guides/compounded-semaglutide-legal-safety-2026) for the full story.

What is orforglipron?

Orforglipron is a daily oral GLP-1 pill (no injection) awaiting FDA approval expected around April 2026. Eli Lilly has announced plans to price it at $149/month via LillyDirect. Clinical trials showed approximately 10-12% average body weight loss. The main side effect is nausea (59% of patients in clinical trials, usually temporary). If approved as anticipated, it would become the leading affordable brand-name option. [Read our complete orforglipron guide](/guides/orforglipron-complete-guide).

Are these rankings influenced by advertising?

No. Telehealth Ally does not accept paid placements, affiliate commissions, or sponsored rankings. Our revenue model is based on lead generation, not provider advertising. Rankings are determined solely by our published scoring methodology.

How often are these rankings updated?

Monthly. We re-evaluate pricing, patient reviews, and provider changes on a rolling basis. The "Last updated" date at the top reflects the most recent comprehensive review.

Do I need a prescription for GLP-1 medications?

Yes. All GLP-1 medications require a prescription from a licensed healthcare provider. Every platform on this list connects you with a licensed prescriber who will evaluate your eligibility based on BMI, health history, and other factors.

What BMI do I need to qualify?

Most providers require a BMI of 27+ with at least one weight-related health condition (hypertension, type 2 diabetes, high cholesterol) or a BMI of 30+. Some providers have slightly different eligibility thresholds. Orforglipron has the same prescribing criteria as other GLP-1 weight loss medications.

Will Medicare cover GLP-1 medications?

The Medicare Bridge program is scheduled to launch July 1, 2026 and would cover GLP-1 medications for weight loss at a $50/month copay — which would be the biggest access expansion in the category's history. Several providers on this list (FORM Health, Calibrate, PlushCare, Sequence) are preparing Medicare navigation. [Read our Medicare GLP-1 coverage guide](/guides/medicare-glp1-coverage-2026-update).

What about CagriSema?

CagriSema (Novo Nordisk's next-generation semaglutide + cagrilintide combination) has been under FDA review since December 2025. As of February 2026, no PDUFA decision date has been publicly disclosed. If approved, it would represent the most effective GLP-1 option yet. We have a [CagriSema patient guide](/guides/cagrisema-patient-guide) and [launch day guide](/guides/cagrisema-launch-day-patient-guide) ready for publication when a decision arrives.

What is a GLP-1 medication?

GLP-1 (glucagon-like peptide-1) receptor agonists are medications originally developed for type 2 diabetes that produce significant weight loss. The most common GLP-1 medications for weight loss are semaglutide (brand names: Wegovy, Wegovy HD) and tirzepatide (brand names: Zepbound, Mounjaro). The newest option under review is orforglipron — a daily oral pill awaiting FDA approval (expected April 2026). They work by mimicking a hormone that reduces appetite and slows gastric emptying. ### What is happening with compounded semaglutide? Compounded semaglutide — the $149/month option that many budget telehealth providers rely on — is under increasing regulatory pressure in 2026. The FDA has issued enforcement actions against 30+ compounding pharmacies. Hims has exited compounding entirely. Several providers (Ro, Henry Meds, Noom, Found) continue to offer compounded options, but availability may tighten further. [Read our compounding guide](/guides/compounded-semaglutide-legal-safety-2026) for the full story. ### What is orforglipron? Orforglipron is a daily oral GLP-1 pill (no injection) awaiting FDA approval expected around April 2026. Eli Lilly has announced plans to price it at $149/month via LillyDirect. Clinical trials showed approximately 10-12% average body weight loss. The main side effect is nausea (59% of patients in clinical trials, usually temporary). If approved as anticipated, it would become the leading affordable brand-name option. [Read our complete orforglipron guide](/guides/orforglipron-complete-guide). ### Are these rankings influenced by advertising? No. Telehealth Ally does not accept paid placements, affiliate commissions, or sponsored rankings. Our revenue model is based on lead generation, not provider advertising. Rankings are determined solely by our published scoring methodology. ### How often are these rankings updated? Monthly. We re-evaluate pricing, patient reviews, and provider changes on a rolling basis. The "Last updated" date at the top reflects the most recent comprehensive review. ### Do I need a prescription for GLP-1 medications? Yes. All GLP-1 medications require a prescription from a licensed healthcare provider. Every platform on this list connects you with a licensed prescriber who will evaluate your eligibility based on BMI, health history, and other factors. ### What BMI do I need to qualify? Most providers require a BMI of 27+ with at least one weight-related health condition (hypertension, type 2 diabetes, high cholesterol) or a BMI of 30+. Some providers have slightly different eligibility thresholds. Orforglipron has the same prescribing criteria as other GLP-1 weight loss medications. ### Will Medicare cover GLP-1 medications? The Medicare Bridge program is scheduled to launch July 1, 2026 and would cover GLP-1 medications for weight loss at a $50/month copay — which would be the biggest access expansion in the category's history. Several providers on this list (FORM Health, Calibrate, PlushCare, Sequence) are preparing Medicare navigation. [Read our Medicare GLP-1 coverage guide](/guides/medicare-glp1-coverage-2026-update). ### What about CagriSema? CagriSema (Novo Nordisk's next-generation semaglutide + cagrilintide combination) has been under FDA review since December 2025. As of February 2026, no PDUFA decision date has been publicly disclosed. If approved, it would represent the most effective GLP-1 option yet. We have a [CagriSema patient guide](/guides/cagrisema-patient-guide) and [launch day guide](/guides/cagrisema-launch-day-patient-guide) ready for publication when a decision arrives.