Amazon One Medical vs Sesame
A detailed head-to-head comparison of Amazon One Medical and Sesame — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Full-service primary care
- Consistent care team that knows your medical history
- Affordable membership, especially for Prime members ($9/mo)
- In-person clinic option in major metros
- Amazon Pharmacy integration with same-day delivery expanding rapidly
- 24/7 virtual access included
Cons
- No compounded GLP-1 options
- No structured weight loss coaching, nutrition programs, or lifestyle support (unlike Found, Calibrate, or WeightWatchers Clinic)
- On-Demand Care does not handle prior authorizations
- Medication cost not included in membership
- Patient complaints about billing issues and unexpected out-of-network charges have been reported
- Not a dedicated weight loss program
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- No subscription, no membership required, no recurring charges
- Lowest consultation cost in the market ($29-$79 per visit)
- Full control over where you fill your prescription
- Orforglipron and Wegovy HD available alongside other branded options
- Broadest medication options
- No long-term commitment
Cons
- You handle medication sourcing, insurance navigation, and pharmacy selection yourself
- No prior authorization assistance
- No coaching, behavioral support, or structured program
- No lab testing included or coordinated
- Clinician quality varies across the marketplace (independent providers, not Sesame employees)
- No ongoing care coordination between visits
Pros & Cons
Peptide Pricing Comparison
| Peptide | Amazon One Medical | Sesame |
|---|---|---|
| Semaglutide | Price unavailable | Price unavailable |
| Tirzepatide | Price unavailable | Price unavailable |
Frequently Asked Questions
Is Amazon One Medical or Sesame better?
Amazon One Medical offers 2 peptides and hybrid consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Amazon One Medical or Sesame?
See the pricing table above for a detailed comparison.