Direct Meds vs Sequence
A detailed head-to-head comparison of Direct Meds and Sequence — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingNo
Shipping5-7 business days
Pros
- Sublingual drop option — no injections required
- Multiple medication formats (injectable + drops)
- Competitive pricing on sublingual options
- Both semaglutide and tirzepatide available
Cons
- Compounded medications only — not FDA-approved
- No insurance accepted
- Limited clinical support beyond prescribing
- Injectable pricing higher than some competitors
- Relatively new with limited reviews
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Founded by obesity medicine specialists
- Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
- Video consultations with experienced clinicians, not just questionnaire-based async reviews
- Prior authorization and insurance appeals support included in membership
- Personalized titration managed through follow-up video visits
Cons
- Higher total cost for cash-pay patients
- The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
- No published independent outcomes data for their patient population
- Insurance navigation success varies
- Less established brand than Hims or Ro
Pros & Cons
Peptide Pricing Comparison
| Peptide | Direct Meds | Sequence |
|---|---|---|
| Semaglutide | Price unavailable | Price unavailable |
| Tirzepatide | Price unavailable | Price unavailable |
Frequently Asked Questions
Is Direct Meds or Sequence better?
Direct Meds offers 2 peptides and async telehealth consultations. Sequence offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Direct Meds or Sequence?
See the pricing table above for a detailed comparison.