Fifty 410 vs PlushCare
A detailed head-to-head comparison of Fifty 410 and PlushCare — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides4
ConsultationAsync Telehealth
Lab TestingNo
Shipping2-6 business days
Pros
- No credit card required until after provider approval
- Multi-month supply ships all at once
- $99/mo equivalent on 3-month semaglutide plan
- Most detailed dose-specific tirzepatide pricing in the peer group
- Outstanding independent review record: 4.8/5 on Trustpilot across 4,381 reviews (the largest review sample in this group)
- No subscriptions, no auto-charges, no membership fees
Cons
- All prescription sales are final
- Binding arbitration clause and class-action waiver (Texas law)
- All medications are compounded
- Compounded GLP-1s face active FDA enforcement pressure; supply and legal landscape can change
- Some states require video/phone consultation before approval (adds friction for fully async-seeking patients)
- Monthly tirzepatide at $299/mo is not as competitively priced as the bundle options suggest
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Backed by publicly traded Accolade
- Insurance-based model
- Video consultations with licensed physicians (not async questionnaire reviews)
- Prescriptions filled at your own pharmacy
- Can manage related health conditions in the same visit (primary care model)
- Available in all 50 states
Cons
- No compounded medications offered
- Generalist physicians, not obesity medicine specialists
- Low membership cost but consultation fees add up without insurance
- Not focused on weight loss
- No proprietary coaching, behavioral program, or weight-loss-specific support
Pros & Cons
Peptide Pricing Comparison
| Peptide | Fifty 410 | PlushCare |
|---|---|---|
| NAD+ | Price unavailable | Not offered |
| Semaglutide | Price unavailable | Price unavailable |
| Sermorelin | Price unavailable | Not offered |
| Tirzepatide | Price unavailable | Price unavailable |
Frequently Asked Questions
Is Fifty 410 or PlushCare better?
Fifty 410 offers 4 peptides and async telehealth consultations. PlushCare offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Fifty 410 or PlushCare?
See the pricing table above for a detailed comparison.