LifeMD vs Sesame
A detailed head-to-head comparison of LifeMD and Sesame — pricing, peptides, consultation models, and patient reviews.
At a Glance
Rating★★★★☆ 4.0/5
Starting Price$299/mo
Peptides2
ConsultationVideo Telehealth
Lab TestingNo
Shipping3-7 business days
Pros
- Available in all 50 states
- Publicly traded (financial transparency)
- Video consultations included
- Competitive GLP-1 pricing
Cons
- Only offers GLP-1 weight loss peptides
- No lab testing included
- No non-weight-loss peptides
- Generic telehealth experience
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- No subscription, no membership required, no recurring charges
- Lowest consultation cost in the market ($29-$79 per visit)
- Full control over where you fill your prescription
- Orforglipron and Wegovy HD available alongside other branded options
- Broadest medication options
- No long-term commitment
Cons
- You handle medication sourcing, insurance navigation, and pharmacy selection yourself
- No prior authorization assistance
- No coaching, behavioral support, or structured program
- No lab testing included or coordinated
- Clinician quality varies across the marketplace (independent providers, not Sesame employees)
- No ongoing care coordination between visits
Pros & Cons
Peptide Pricing Comparison
| Peptide | LifeMD | Sesame |
|---|---|---|
| Semaglutide | $299/monthly | Price unavailable |
| Tirzepatide | $399/monthly | Price unavailable |
Frequently Asked Questions
Is LifeMD or Sesame better?
LifeMD offers 2 peptides with a 4/5 rating and video telehealth consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, LifeMD or Sesame?
See the pricing table above for a detailed comparison.