How do Optavia and Sesame compare on pricing?

Optavia starts at varying prices. Sesame starts at varying prices. Actual cost depends on the medication, dose, and billing cycle you choose.

Optavia vs Sesame

A detailed head-to-head comparison of Optavia and Sesame — pricing, peptides, consultation models, and patient reviews.

At a Glance

	Optavia	Sesame
Rating	No reviews	No reviews
Starting Price	N/A	N/A
Peptides Offered	2	2
Consultation	Async Telehealth	Async Telehealth
Lab Testing	No	Yes
Shipping	3-5 business days	3-5 business days
Headquarters	Baltimore, MD	New York, NY
Founded	2017	2019

Optavia

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationAsync Telehealth

Lab TestingNo

Shipping3-5 business days

Pros

Highly structured meal replacement system with decades of Medifast research behind the Fuelings products
Coach community provides strong accountability, community, and daily behavioral support
Combining a low-calorie structured diet with GLP-1 therapy may produce greater caloric reduction than either alone
Fuelings system removes meal decision fatigue
Large, established coach network with broad geographic coverage

Cons

Coaches are not licensed clinicians
The GLP-1 medical pathway runs through a separate third-party telehealth platform, creating a fragmented care experience where coach and prescribing clinician operate independently
Total combined cost (Fuelings + GLP-1 medication) can exceed $600–$800/month, making this among the more expensive weight management options
Fuelings program uses a multi-level distribution model; coach incentives are tied to product sales, which is a structural conflict of interest patients should understand
Not suitable for patients who want a single integrated clinical program

Sesame

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationAsync Telehealth

Lab TestingYes

Shipping3-5 business days

Pros

No subscription, no membership required, no recurring charges
Lowest consultation cost in the market ($29-$79 per visit)
Full control over where you fill your prescription
Orforglipron and Wegovy HD available alongside other branded options
Broadest medication options
No long-term commitment

Cons

You handle medication sourcing, insurance navigation, and pharmacy selection yourself
No prior authorization assistance
No coaching, behavioral support, or structured program
No lab testing included or coordinated
Clinician quality varies across the marketplace (independent providers, not Sesame employees)
No ongoing care coordination between visits

Pros & Cons

Optavia

Pros

+Highly structured meal replacement system with decades of Medifast research behind the Fuelings products
+Coach community provides strong accountability, community, and daily behavioral support
+Combining a low-calorie structured diet with GLP-1 therapy may produce greater caloric reduction than either alone
+Fuelings system removes meal decision fatigue
+Large, established coach network with broad geographic coverage

Cons

-Coaches are not licensed clinicians
-The GLP-1 medical pathway runs through a separate third-party telehealth platform, creating a fragmented care experience where coach and prescribing clinician operate independently
-Total combined cost (Fuelings + GLP-1 medication) can exceed $600–$800/month, making this among the more expensive weight management options
-Fuelings program uses a multi-level distribution model; coach incentives are tied to product sales, which is a structural conflict of interest patients should understand
-Not suitable for patients who want a single integrated clinical program

Sesame

Pros

+No subscription, no membership required, no recurring charges
+Lowest consultation cost in the market ($29-$79 per visit)
+Full control over where you fill your prescription
+Orforglipron and Wegovy HD available alongside other branded options
+Broadest medication options
+No long-term commitment

Cons

-You handle medication sourcing, insurance navigation, and pharmacy selection yourself
-No prior authorization assistance
-No coaching, behavioral support, or structured program
-No lab testing included or coordinated
-Clinician quality varies across the marketplace (independent providers, not Sesame employees)
-No ongoing care coordination between visits

Peptide Pricing Comparison

Peptide	Optavia	Sesame
Semaglutide	Price unavailable	Price unavailable
Tirzepatide	Price unavailable	Price unavailable

Frequently Asked Questions

Is Optavia or Sesame better?

Optavia offers 2 peptides and async telehealth consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Optavia or Sesame?

See the pricing table above for a detailed comparison.

Learn More

Optavia

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Sesame

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