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Paloma Health vs Sequence

A detailed head-to-head comparison of Paloma Health and Sequence — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingYes
Shipping3-5 business days

Pros

  • Comprehensive thyroid testing included in membership
  • Insurance accepted for consultations, which reduces out-of-pocket cost compared to most GLP-1 platforms
  • Thyroid optimization before or alongside GLP-1 prescribing is clinically more thorough than platforms that ignore thyroid status
  • Specialist-level thyroid knowledge; providers understand the nuances of T3/T4 ratios and symptom-lab discordance
  • At-home lab testing removes a significant barrier for patients who struggle to access phlebotomy services
  • Addresses a frequently missed root cause of weight-loss resistance

Cons

  • Primarily a thyroid platform; patients without thyroid concerns may find it a poor fit for standalone weight management
  • GLP-1 prescribing is a secondary offering
  • Membership fees plus medication costs can add up; the total may exceed single-service weight-loss platforms
  • State availability is broad but not universal
  • Patients without a thyroid diagnosis may find the intake process more involved than they expected for weight management alone
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Founded by obesity medicine specialists
  • Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
  • Video consultations with experienced clinicians, not just questionnaire-based async reviews
  • Prior authorization and insurance appeals support included in membership
  • Personalized titration managed through follow-up video visits

Cons

  • Higher total cost for cash-pay patients
  • The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
  • No published independent outcomes data for their patient population
  • Insurance navigation success varies
  • Less established brand than Hims or Ro

Pros & Cons

Peptide Pricing Comparison

PeptidePaloma HealthSequence
SemaglutidePrice unavailablePrice unavailable
TirzepatidePrice unavailablePrice unavailable

Frequently Asked Questions

Is Paloma Health or Sequence better?

Paloma Health offers 2 peptides and hybrid consultations. Sequence offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Paloma Health or Sequence?

See the pricing table above for a detailed comparison.

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