Paloma Health vs Sesame
A detailed head-to-head comparison of Paloma Health and Sesame — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingYes
Shipping3-5 business days
Pros
- Comprehensive thyroid testing included in membership
- Insurance accepted for consultations, which reduces out-of-pocket cost compared to most GLP-1 platforms
- Thyroid optimization before or alongside GLP-1 prescribing is clinically more thorough than platforms that ignore thyroid status
- Specialist-level thyroid knowledge; providers understand the nuances of T3/T4 ratios and symptom-lab discordance
- At-home lab testing removes a significant barrier for patients who struggle to access phlebotomy services
- Addresses a frequently missed root cause of weight-loss resistance
Cons
- Primarily a thyroid platform; patients without thyroid concerns may find it a poor fit for standalone weight management
- GLP-1 prescribing is a secondary offering
- Membership fees plus medication costs can add up; the total may exceed single-service weight-loss platforms
- State availability is broad but not universal
- Patients without a thyroid diagnosis may find the intake process more involved than they expected for weight management alone
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- No subscription, no membership required, no recurring charges
- Lowest consultation cost in the market ($29-$79 per visit)
- Full control over where you fill your prescription
- Orforglipron and Wegovy HD available alongside other branded options
- Broadest medication options
- No long-term commitment
Cons
- You handle medication sourcing, insurance navigation, and pharmacy selection yourself
- No prior authorization assistance
- No coaching, behavioral support, or structured program
- No lab testing included or coordinated
- Clinician quality varies across the marketplace (independent providers, not Sesame employees)
- No ongoing care coordination between visits
Pros & Cons
Peptide Pricing Comparison
| Peptide | Paloma Health | Sesame |
|---|---|---|
| Semaglutide | Price unavailable | Price unavailable |
| Tirzepatide | Price unavailable | Price unavailable |
Frequently Asked Questions
Is Paloma Health or Sesame better?
Paloma Health offers 2 peptides and hybrid consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Paloma Health or Sesame?
See the pricing table above for a detailed comparison.