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PlushCare vs Sequence

A detailed head-to-head comparison of PlushCare and Sequence — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Backed by publicly traded Accolade
  • Insurance-based model
  • Video consultations with licensed physicians (not async questionnaire reviews)
  • Prescriptions filled at your own pharmacy
  • Can manage related health conditions in the same visit (primary care model)
  • Available in all 50 states

Cons

  • No compounded medications offered
  • Generalist physicians, not obesity medicine specialists
  • Low membership cost but consultation fees add up without insurance
  • Not focused on weight loss
  • No proprietary coaching, behavioral program, or weight-loss-specific support
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Founded by obesity medicine specialists
  • Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
  • Video consultations with experienced clinicians, not just questionnaire-based async reviews
  • Prior authorization and insurance appeals support included in membership
  • Personalized titration managed through follow-up video visits

Cons

  • Higher total cost for cash-pay patients
  • The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
  • No published independent outcomes data for their patient population
  • Insurance navigation success varies
  • Less established brand than Hims or Ro

Pros & Cons

Peptide Pricing Comparison

PeptidePlushCareSequence
SemaglutidePrice unavailablePrice unavailable
TirzepatidePrice unavailablePrice unavailable

Frequently Asked Questions

Is PlushCare or Sequence better?

PlushCare offers 2 peptides and hybrid consultations. Sequence offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, PlushCare or Sequence?

See the pricing table above for a detailed comparison.