Skip to main content

Ro vs Sesame

A detailed head-to-head comparison of Ro and Sesame — pricing, peptides, consultation models, and patient reviews.

At a Glance

Rating★★★★☆ 4.0/5
Starting Price$149/mo
Peptides2
ConsultationAsync Telehealth
Lab TestingNo
Shipping3-5 business days

Pros

  • Competitive compounded semaglutide pricing (from $149/mo)
  • Large established platform with millions of patients
  • Free ongoing provider messaging
  • Body program includes metabolic health coaching

Cons

  • No video consultations — async only
  • No lab testing included
  • Only offers GLP-1 weight loss medications
  • Compounded medications not FDA-approved as finished products
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingYes
Shipping3-5 business days

Pros

  • No subscription, no membership required, no recurring charges
  • Lowest consultation cost in the market ($29-$79 per visit)
  • Full control over where you fill your prescription
  • Orforglipron and Wegovy HD available alongside other branded options
  • Broadest medication options
  • No long-term commitment

Cons

  • You handle medication sourcing, insurance navigation, and pharmacy selection yourself
  • No prior authorization assistance
  • No coaching, behavioral support, or structured program
  • No lab testing included or coordinated
  • Clinician quality varies across the marketplace (independent providers, not Sesame employees)
  • No ongoing care coordination between visits

Pros & Cons

Peptide Pricing Comparison

PeptideRoSesame
Semaglutide
$149/monthly
Price unavailable
Tirzepatide
$399/monthly
Price unavailable

Frequently Asked Questions

Is Ro or Sesame better?

Ro offers 2 peptides with a 4/5 rating and async telehealth consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Ro or Sesame?

See the pricing table above for a detailed comparison.