How do Sequence and Sesame compare on pricing?

Sequence starts at varying prices. Sesame starts at varying prices. Actual cost depends on the medication, dose, and billing cycle you choose.

Sequence vs Sesame

A detailed head-to-head comparison of Sequence and Sesame — pricing, peptides, consultation models, and patient reviews.

At a Glance

	Sequence	Sesame
Rating	No reviews	No reviews
Starting Price	N/A	N/A
Peptides Offered	2	2
Consultation	Hybrid	Async Telehealth
Lab Testing	No	Yes
Shipping	3-5 business days	3-5 business days
Headquarters	New York, NY	New York, NY
Founded	2021	2019

Sequence

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationHybrid

Lab TestingNo

Shipping3-5 business days

Pros

Founded by obesity medicine specialists
Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
Video consultations with experienced clinicians, not just questionnaire-based async reviews
Prior authorization and insurance appeals support included in membership
Personalized titration managed through follow-up video visits

Cons

Higher total cost for cash-pay patients
The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
No published independent outcomes data for their patient population
Insurance navigation success varies
Less established brand than Hims or Ro

Sesame

RatingNo reviews

Starting PriceN/A

Peptides2

ConsultationAsync Telehealth

Lab TestingYes

Shipping3-5 business days

Pros

No subscription, no membership required, no recurring charges
Lowest consultation cost in the market ($29-$79 per visit)
Full control over where you fill your prescription
Orforglipron and Wegovy HD available alongside other branded options
Broadest medication options
No long-term commitment

Cons

You handle medication sourcing, insurance navigation, and pharmacy selection yourself
No prior authorization assistance
No coaching, behavioral support, or structured program
No lab testing included or coordinated
Clinician quality varies across the marketplace (independent providers, not Sesame employees)
No ongoing care coordination between visits

Pros & Cons

Sequence

Pros

+Founded by obesity medicine specialists
+Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
+Video consultations with experienced clinicians, not just questionnaire-based async reviews
+Prior authorization and insurance appeals support included in membership
+Personalized titration managed through follow-up video visits

Cons

-Higher total cost for cash-pay patients
-The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
-No published independent outcomes data for their patient population
-Insurance navigation success varies
-Less established brand than Hims or Ro

Sesame

Pros

+No subscription, no membership required, no recurring charges
+Lowest consultation cost in the market ($29-$79 per visit)
+Full control over where you fill your prescription
+Orforglipron and Wegovy HD available alongside other branded options
+Broadest medication options
+No long-term commitment

Cons

-You handle medication sourcing, insurance navigation, and pharmacy selection yourself
-No prior authorization assistance
-No coaching, behavioral support, or structured program
-No lab testing included or coordinated
-Clinician quality varies across the marketplace (independent providers, not Sesame employees)
-No ongoing care coordination between visits

Peptide Pricing Comparison

Peptide	Sequence	Sesame
Semaglutide	Price unavailable	Price unavailable
Tirzepatide	Price unavailable	Price unavailable

Frequently Asked Questions

Is Sequence or Sesame better?

Sequence offers 2 peptides and hybrid consultations. Sesame offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Sequence or Sesame?

See the pricing table above for a detailed comparison.

Learn More

Sequence

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Sesame

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