Sequence vs Shed
A detailed head-to-head comparison of Sequence and Shed — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Founded by obesity medicine specialists
- Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
- Video consultations with experienced clinicians, not just questionnaire-based async reviews
- Prior authorization and insurance appeals support included in membership
- Personalized titration managed through follow-up video visits
Cons
- Higher total cost for cash-pay patients
- The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
- No published independent outcomes data for their patient population
- Insurance navigation success varies
- Less established brand than Hims or Ro
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Can coordinate GLP-1 with TRT under one provider
- Video consultations available, not just async messaging
- Straightforward single-price billing with no separate membership fees
- Men's health specialization means providers are familiar with hormonal interactions that affect weight
- HSA/FSA eligible
Cons
- Men-only positioning may exclude patients who would otherwise benefit from the service
- Available in only 42 states
- No brand-name GLP-1 medications available
- No dietitian access or dedicated weight loss coaching
- Newer to weight management (expanded from TRT/ED in 2024)
- Smaller patient base means less operational scale and potentially less refined processes
Pros & Cons
Peptide Pricing Comparison
| Peptide | Sequence | Shed |
|---|---|---|
| Semaglutide | Price unavailable | Price unavailable |
| Tirzepatide | Price unavailable | Price unavailable |
Frequently Asked Questions
Is Sequence or Shed better?
Sequence offers 2 peptides and hybrid consultations. Shed offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Sequence or Shed?
See the pricing table above for a detailed comparison.