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Sequence vs Yucca Health

A detailed head-to-head comparison of Sequence and Yucca Health — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • Founded by obesity medicine specialists
  • Insurance-first approach can save patients hundreds per month on brand-name GLP-1 medications
  • Video consultations with experienced clinicians, not just questionnaire-based async reviews
  • Prior authorization and insurance appeals support included in membership
  • Personalized titration managed through follow-up video visits

Cons

  • Higher total cost for cash-pay patients
  • The $99/month membership is charged on top of medication costs (unlike all-inclusive platforms)
  • No published independent outcomes data for their patient population
  • Insurance navigation success varies
  • Less established brand than Hims or Ro
RatingNo reviews
Starting PriceN/A
Peptides4
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • 934 Trustpilot reviews at 4.6/5
  • UPS 2-Day Air expedited shipping on all plans, standard (not an upgrade)
  • Onboarding call included post-approval
  • First-month $100 discount for new patients
  • Buy-now-pay-later available on 6-month plans (Klarna, Affirm, Afterpay)
  • 24/7 patient support

Cons

  • Mid-to-high pricing: $275/mo (semaglutide monthly), $385/mo (tirzepatide monthly)
  • Auto-subscription with renewal
  • No refunds once medication has shipped
  • No insurance billing
  • HSA/FSA documentation (itemized receipts, letters of medical necessity) not provided
  • No brand-name GLP-1 options

Pros & Cons

Peptide Pricing Comparison

PeptideSequenceYucca Health
NAD+Not offeredPrice unavailable
SemaglutidePrice unavailablePrice unavailable
SermorelinNot offeredPrice unavailable
TirzepatidePrice unavailablePrice unavailable

Frequently Asked Questions

Is Sequence or Yucca Health better?

Sequence offers 2 peptides and hybrid consultations. Yucca Health offers 4 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Sequence or Yucca Health?

See the pricing table above for a detailed comparison.

Learn More