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Sesame vs Yucca Health

A detailed head-to-head comparison of Sesame and Yucca Health — pricing, peptides, consultation models, and patient reviews.

At a Glance

RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingYes
Shipping3-5 business days

Pros

  • No subscription, no membership required, no recurring charges
  • Lowest consultation cost in the market ($29-$79 per visit)
  • Full control over where you fill your prescription
  • Orforglipron and Wegovy HD available alongside other branded options
  • Broadest medication options
  • No long-term commitment

Cons

  • You handle medication sourcing, insurance navigation, and pharmacy selection yourself
  • No prior authorization assistance
  • No coaching, behavioral support, or structured program
  • No lab testing included or coordinated
  • Clinician quality varies across the marketplace (independent providers, not Sesame employees)
  • No ongoing care coordination between visits
RatingNo reviews
Starting PriceN/A
Peptides4
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days

Pros

  • 934 Trustpilot reviews at 4.6/5
  • UPS 2-Day Air expedited shipping on all plans, standard (not an upgrade)
  • Onboarding call included post-approval
  • First-month $100 discount for new patients
  • Buy-now-pay-later available on 6-month plans (Klarna, Affirm, Afterpay)
  • 24/7 patient support

Cons

  • Mid-to-high pricing: $275/mo (semaglutide monthly), $385/mo (tirzepatide monthly)
  • Auto-subscription with renewal
  • No refunds once medication has shipped
  • No insurance billing
  • HSA/FSA documentation (itemized receipts, letters of medical necessity) not provided
  • No brand-name GLP-1 options

Pros & Cons

Peptide Pricing Comparison

PeptideSesameYucca Health
NAD+Not offeredPrice unavailable
SemaglutidePrice unavailablePrice unavailable
SermorelinNot offeredPrice unavailable
TirzepatidePrice unavailablePrice unavailable

Frequently Asked Questions

Is Sesame or Yucca Health better?

Sesame offers 2 peptides and async telehealth consultations. Yucca Health offers 4 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.

Which is cheaper, Sesame or Yucca Health?

See the pricing table above for a detailed comparison.