Amazon One Medical vs Defy Medical
A detailed head-to-head comparison of Amazon One Medical and Defy Medical — pricing, peptides, consultation models, and patient reviews.
At a Glance
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Full-service primary care
- Consistent care team that knows your medical history
- Affordable membership, especially for Prime members ($9/mo)
- In-person clinic option in major metros
- Amazon Pharmacy integration with same-day delivery expanding rapidly
- 24/7 virtual access included
Cons
- No compounded GLP-1 options
- No structured weight loss coaching, nutrition programs, or lifestyle support (unlike Found, Calibrate, or WeightWatchers Clinic)
- On-Demand Care does not handle prior authorizations
- Medication cost not included in membership
- Patient complaints about billing issues and unexpected out-of-network charges have been reported
- Not a dedicated weight loss program
Rating★★★★☆ 4.1/5
Starting Price$120/mo
Peptides32
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- Longest-running telehealth peptide provider
- Wide peptide and hormone catalog
- Video consultations with experienced physicians
- Comprehensive lab panels included
Cons
- Higher initial consultation fee (~$250)
- Separate lab and medication costs
- Not the cheapest per-medication pricing
Pros & Cons
Peptide Pricing Comparison
| Peptide | Amazon One Medical | Defy Medical |
|---|---|---|
| AOD-9604 | Not offered | $160/monthly |
| BPC-157 | Not offered | $165/monthly |
| CJC-1295 / Ipamorelin | Not offered | $180/monthly |
| Dihexa | Not offered | $200/monthly |
| Epithalon | Not offered | $250/per-cycle |
| FOXO4-DRI | Not offered | $450/per-cycle |
| GHK-Cu | Not offered | $145/monthly |
| GHRP-2 | Not offered | $150/monthly |
| GHRP-6 | Not offered | $150/monthly |
| Gonadorelin | Not offered | $140/monthly |
| IGF-1 LR3 | Not offered | $250/monthly |
| Kisspeptin | Not offered | $200/monthly |
| KPV | Not offered | $130/monthly |
| Liraglutide | Not offered | $220/monthly |
| LL-37 | Not offered | $180/monthly |
| Melanotan II | Not offered | $120/per-vial |
| MK-677 | Not offered | $120/monthly |
| MOTS-c | Not offered | $220/monthly |
| NAD+ | Not offered | $220/monthly |
| Oxytocin | Not offered | $120/monthly |
| P21 | Not offered | $180/monthly |
| Pentadeca Arginate | Not offered | $175/monthly |
| PT-141 | Not offered | $150/per-vial |
| Retatrutide | Not offered | $450/monthly |
| Selank | Not offered | $120/monthly |
| Semaglutide | Price unavailable | $280/monthly |
| Semax | Not offered | $120/monthly |
| Sermorelin | Not offered | $175/monthly |
| SS-31 | Not offered | $280/monthly |
| TB-500 | Not offered | $180/monthly |
| Tesamorelin | Not offered | $350/monthly |
| Thymosin Alpha-1 | Not offered | $220/monthly |
| Tirzepatide | Price unavailable | Not offered |
Frequently Asked Questions
Is Amazon One Medical or Defy Medical better?
Amazon One Medical offers 2 peptides and hybrid consultations. Defy Medical offers 32 peptides with a 4.1/5 rating and video telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Amazon One Medical or Defy Medical?
See the pricing table above for a detailed comparison.