Defy Medical vs Optavia
A detailed head-to-head comparison of Defy Medical and Optavia — pricing, peptides, consultation models, and patient reviews.
At a Glance
Rating★★★★☆ 4.1/5
Starting Price$120/mo
Peptides32
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- Longest-running telehealth peptide provider
- Wide peptide and hormone catalog
- Video consultations with experienced physicians
- Comprehensive lab panels included
Cons
- Higher initial consultation fee (~$250)
- Separate lab and medication costs
- Not the cheapest per-medication pricing
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationAsync Telehealth
Lab TestingNo
Shipping3-5 business days
Pros
- Highly structured meal replacement system with decades of Medifast research behind the Fuelings products
- Coach community provides strong accountability, community, and daily behavioral support
- Combining a low-calorie structured diet with GLP-1 therapy may produce greater caloric reduction than either alone
- Fuelings system removes meal decision fatigue
- Large, established coach network with broad geographic coverage
Cons
- Coaches are not licensed clinicians
- The GLP-1 medical pathway runs through a separate third-party telehealth platform, creating a fragmented care experience where coach and prescribing clinician operate independently
- Total combined cost (Fuelings + GLP-1 medication) can exceed $600–$800/month, making this among the more expensive weight management options
- Fuelings program uses a multi-level distribution model; coach incentives are tied to product sales, which is a structural conflict of interest patients should understand
- Not suitable for patients who want a single integrated clinical program
Pros & Cons
Peptide Pricing Comparison
| Peptide | Defy Medical | Optavia |
|---|---|---|
| AOD-9604 | $160/monthly | Not offered |
| BPC-157 | $165/monthly | Not offered |
| CJC-1295 / Ipamorelin | $180/monthly | Not offered |
| Dihexa | $200/monthly | Not offered |
| Epithalon | $250/per-cycle | Not offered |
| FOXO4-DRI | $450/per-cycle | Not offered |
| GHK-Cu | $145/monthly | Not offered |
| GHRP-2 | $150/monthly | Not offered |
| GHRP-6 | $150/monthly | Not offered |
| Gonadorelin | $140/monthly | Not offered |
| IGF-1 LR3 | $250/monthly | Not offered |
| Kisspeptin | $200/monthly | Not offered |
| KPV | $130/monthly | Not offered |
| Liraglutide | $220/monthly | Not offered |
| LL-37 | $180/monthly | Not offered |
| Melanotan II | $120/per-vial | Not offered |
| MK-677 | $120/monthly | Not offered |
| MOTS-c | $220/monthly | Not offered |
| NAD+ | $220/monthly | Not offered |
| Oxytocin | $120/monthly | Not offered |
| P21 | $180/monthly | Not offered |
| Pentadeca Arginate | $175/monthly | Not offered |
| PT-141 | $150/per-vial | Not offered |
| Retatrutide | $450/monthly | Not offered |
| Selank | $120/monthly | Not offered |
| Semaglutide | $280/monthly | Price unavailable |
| Semax | $120/monthly | Not offered |
| Sermorelin | $175/monthly | Not offered |
| SS-31 | $280/monthly | Not offered |
| TB-500 | $180/monthly | Not offered |
| Tesamorelin | $350/monthly | Not offered |
| Thymosin Alpha-1 | $220/monthly | Not offered |
| Tirzepatide | Not offered | Price unavailable |
Frequently Asked Questions
Is Defy Medical or Optavia better?
Defy Medical offers 32 peptides with a 4.1/5 rating and video telehealth consultations. Optavia offers 2 peptides and async telehealth consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Defy Medical or Optavia?
See the pricing table above for a detailed comparison.