Defy Medical vs Paloma Health
A detailed head-to-head comparison of Defy Medical and Paloma Health — pricing, peptides, consultation models, and patient reviews.
At a Glance
Rating★★★★☆ 4.1/5
Starting Price$120/mo
Peptides32
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- Longest-running telehealth peptide provider
- Wide peptide and hormone catalog
- Video consultations with experienced physicians
- Comprehensive lab panels included
Cons
- Higher initial consultation fee (~$250)
- Separate lab and medication costs
- Not the cheapest per-medication pricing
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingYes
Shipping3-5 business days
Pros
- Comprehensive thyroid testing included in membership
- Insurance accepted for consultations, which reduces out-of-pocket cost compared to most GLP-1 platforms
- Thyroid optimization before or alongside GLP-1 prescribing is clinically more thorough than platforms that ignore thyroid status
- Specialist-level thyroid knowledge; providers understand the nuances of T3/T4 ratios and symptom-lab discordance
- At-home lab testing removes a significant barrier for patients who struggle to access phlebotomy services
- Addresses a frequently missed root cause of weight-loss resistance
Cons
- Primarily a thyroid platform; patients without thyroid concerns may find it a poor fit for standalone weight management
- GLP-1 prescribing is a secondary offering
- Membership fees plus medication costs can add up; the total may exceed single-service weight-loss platforms
- State availability is broad but not universal
- Patients without a thyroid diagnosis may find the intake process more involved than they expected for weight management alone
Pros & Cons
Peptide Pricing Comparison
| Peptide | Defy Medical | Paloma Health |
|---|---|---|
| AOD-9604 | $160/monthly | Not offered |
| BPC-157 | $165/monthly | Not offered |
| CJC-1295 / Ipamorelin | $180/monthly | Not offered |
| Dihexa | $200/monthly | Not offered |
| Epithalon | $250/per-cycle | Not offered |
| FOXO4-DRI | $450/per-cycle | Not offered |
| GHK-Cu | $145/monthly | Not offered |
| GHRP-2 | $150/monthly | Not offered |
| GHRP-6 | $150/monthly | Not offered |
| Gonadorelin | $140/monthly | Not offered |
| IGF-1 LR3 | $250/monthly | Not offered |
| Kisspeptin | $200/monthly | Not offered |
| KPV | $130/monthly | Not offered |
| Liraglutide | $220/monthly | Not offered |
| LL-37 | $180/monthly | Not offered |
| Melanotan II | $120/per-vial | Not offered |
| MK-677 | $120/monthly | Not offered |
| MOTS-c | $220/monthly | Not offered |
| NAD+ | $220/monthly | Not offered |
| Oxytocin | $120/monthly | Not offered |
| P21 | $180/monthly | Not offered |
| Pentadeca Arginate | $175/monthly | Not offered |
| PT-141 | $150/per-vial | Not offered |
| Retatrutide | $450/monthly | Not offered |
| Selank | $120/monthly | Not offered |
| Semaglutide | $280/monthly | Price unavailable |
| Semax | $120/monthly | Not offered |
| Sermorelin | $175/monthly | Not offered |
| SS-31 | $280/monthly | Not offered |
| TB-500 | $180/monthly | Not offered |
| Tesamorelin | $350/monthly | Not offered |
| Thymosin Alpha-1 | $220/monthly | Not offered |
| Tirzepatide | Not offered | Price unavailable |
Frequently Asked Questions
Is Defy Medical or Paloma Health better?
Defy Medical offers 32 peptides with a 4.1/5 rating and video telehealth consultations. Paloma Health offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Defy Medical or Paloma Health?
See the pricing table above for a detailed comparison.