Defy Medical vs PlushCare
A detailed head-to-head comparison of Defy Medical and PlushCare — pricing, peptides, consultation models, and patient reviews.
At a Glance
Rating★★★★☆ 4.1/5
Starting Price$120/mo
Peptides32
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- Longest-running telehealth peptide provider
- Wide peptide and hormone catalog
- Video consultations with experienced physicians
- Comprehensive lab panels included
Cons
- Higher initial consultation fee (~$250)
- Separate lab and medication costs
- Not the cheapest per-medication pricing
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Backed by publicly traded Accolade
- Insurance-based model
- Video consultations with licensed physicians (not async questionnaire reviews)
- Prescriptions filled at your own pharmacy
- Can manage related health conditions in the same visit (primary care model)
- Available in all 50 states
Cons
- No compounded medications offered
- Generalist physicians, not obesity medicine specialists
- Low membership cost but consultation fees add up without insurance
- Not focused on weight loss
- No proprietary coaching, behavioral program, or weight-loss-specific support
Pros & Cons
Peptide Pricing Comparison
| Peptide | Defy Medical | PlushCare |
|---|---|---|
| AOD-9604 | $160/monthly | Not offered |
| BPC-157 | $165/monthly | Not offered |
| CJC-1295 / Ipamorelin | $180/monthly | Not offered |
| Dihexa | $200/monthly | Not offered |
| Epithalon | $250/per-cycle | Not offered |
| FOXO4-DRI | $450/per-cycle | Not offered |
| GHK-Cu | $145/monthly | Not offered |
| GHRP-2 | $150/monthly | Not offered |
| GHRP-6 | $150/monthly | Not offered |
| Gonadorelin | $140/monthly | Not offered |
| IGF-1 LR3 | $250/monthly | Not offered |
| Kisspeptin | $200/monthly | Not offered |
| KPV | $130/monthly | Not offered |
| Liraglutide | $220/monthly | Not offered |
| LL-37 | $180/monthly | Not offered |
| Melanotan II | $120/per-vial | Not offered |
| MK-677 | $120/monthly | Not offered |
| MOTS-c | $220/monthly | Not offered |
| NAD+ | $220/monthly | Not offered |
| Oxytocin | $120/monthly | Not offered |
| P21 | $180/monthly | Not offered |
| Pentadeca Arginate | $175/monthly | Not offered |
| PT-141 | $150/per-vial | Not offered |
| Retatrutide | $450/monthly | Not offered |
| Selank | $120/monthly | Not offered |
| Semaglutide | $280/monthly | Price unavailable |
| Semax | $120/monthly | Not offered |
| Sermorelin | $175/monthly | Not offered |
| SS-31 | $280/monthly | Not offered |
| TB-500 | $180/monthly | Not offered |
| Tesamorelin | $350/monthly | Not offered |
| Thymosin Alpha-1 | $220/monthly | Not offered |
| Tirzepatide | Not offered | Price unavailable |
Frequently Asked Questions
Is Defy Medical or PlushCare better?
Defy Medical offers 32 peptides with a 4.1/5 rating and video telehealth consultations. PlushCare offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Defy Medical or PlushCare?
See the pricing table above for a detailed comparison.