Defy Medical vs Shed
A detailed head-to-head comparison of Defy Medical and Shed — pricing, peptides, consultation models, and patient reviews.
At a Glance
Rating★★★★☆ 4.1/5
Starting Price$120/mo
Peptides32
ConsultationVideo Telehealth
Lab TestingYes
Shipping3-5 business days
Pros
- Longest-running telehealth peptide provider
- Wide peptide and hormone catalog
- Video consultations with experienced physicians
- Comprehensive lab panels included
Cons
- Higher initial consultation fee (~$250)
- Separate lab and medication costs
- Not the cheapest per-medication pricing
RatingNo reviews
Starting PriceN/A
Peptides2
ConsultationHybrid
Lab TestingNo
Shipping3-5 business days
Pros
- Can coordinate GLP-1 with TRT under one provider
- Video consultations available, not just async messaging
- Straightforward single-price billing with no separate membership fees
- Men's health specialization means providers are familiar with hormonal interactions that affect weight
- HSA/FSA eligible
Cons
- Men-only positioning may exclude patients who would otherwise benefit from the service
- Available in only 42 states
- No brand-name GLP-1 medications available
- No dietitian access or dedicated weight loss coaching
- Newer to weight management (expanded from TRT/ED in 2024)
- Smaller patient base means less operational scale and potentially less refined processes
Pros & Cons
Peptide Pricing Comparison
| Peptide | Defy Medical | Shed |
|---|---|---|
| AOD-9604 | $160/monthly | Not offered |
| BPC-157 | $165/monthly | Not offered |
| CJC-1295 / Ipamorelin | $180/monthly | Not offered |
| Dihexa | $200/monthly | Not offered |
| Epithalon | $250/per-cycle | Not offered |
| FOXO4-DRI | $450/per-cycle | Not offered |
| GHK-Cu | $145/monthly | Not offered |
| GHRP-2 | $150/monthly | Not offered |
| GHRP-6 | $150/monthly | Not offered |
| Gonadorelin | $140/monthly | Not offered |
| IGF-1 LR3 | $250/monthly | Not offered |
| Kisspeptin | $200/monthly | Not offered |
| KPV | $130/monthly | Not offered |
| Liraglutide | $220/monthly | Not offered |
| LL-37 | $180/monthly | Not offered |
| Melanotan II | $120/per-vial | Not offered |
| MK-677 | $120/monthly | Not offered |
| MOTS-c | $220/monthly | Not offered |
| NAD+ | $220/monthly | Not offered |
| Oxytocin | $120/monthly | Not offered |
| P21 | $180/monthly | Not offered |
| Pentadeca Arginate | $175/monthly | Not offered |
| PT-141 | $150/per-vial | Not offered |
| Retatrutide | $450/monthly | Not offered |
| Selank | $120/monthly | Not offered |
| Semaglutide | $280/monthly | Price unavailable |
| Semax | $120/monthly | Not offered |
| Sermorelin | $175/monthly | Not offered |
| SS-31 | $280/monthly | Not offered |
| TB-500 | $180/monthly | Not offered |
| Tesamorelin | $350/monthly | Not offered |
| Thymosin Alpha-1 | $220/monthly | Not offered |
| Tirzepatide | Not offered | Price unavailable |
Frequently Asked Questions
Is Defy Medical or Shed better?
Defy Medical offers 32 peptides with a 4.1/5 rating and video telehealth consultations. Shed offers 2 peptides and hybrid consultations. The best choice depends on which peptides you need, your budget, and preferred consultation model.
Which is cheaper, Defy Medical or Shed?
See the pricing table above for a detailed comparison.